Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Amelx  amelogenin, X-linked   (Synonyms: Amel, Amg, M100888, Rgsc888)
Results	Reference
1	J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365
1	J:245023 Cantu C, Pagella P, Shajiei TD, Zimmerli D, Valenta T, Hausmann G, Basler K, Mitsiadis TA, A cytoplasmic role of Wnt/beta-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation. Sci Signal. 2017 Feb 07;10(465)
1	J:199298 Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA, The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development. 2013 Aug;140(16):3348-59
1*	J:40646 Diekwisch TG, Ware J, Fincham AG, Zeichner-David M, Immunohistochemical similarities and differences between amelogenin and tuftelin gene products during tooth development. J Histochem Cytochem. 1997 Jun;45(6):859-66
1	J:308456 Eliason S, Sharp T, Sweat M, Sweat YY, Amendt BA, Ectodermal Organ Development Is Regulated by a microRNA-26b-Lef-1-Wnt Signaling Axis. Front Physiol. 2020;11:780
1	J:327958 Eliason S, Su D, Pinho F, Sun Z, Zhang Z, Li X, Sweat M, Venugopalan SR, He B, Bustin M, Amendt BA, HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. J Biol Chem. 2022 Jul 21;298(9):102295
1*	J:279055 He B, Chiba Y, Li H, de Vega S, Tanaka K, Yoshizaki K, Ishijima M, Yuasa K, Ishikawa M, Rhodes C, Sakai K, Zhang P, Fukumoto S, Zhou X, Yamada Y, Identification of the Novel Tooth-Specific Transcription Factor AmeloD. J Dent Res. 2019 Feb;98(2):234-241
1	J:182873 Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD, PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci. 2011 Mar 1;124(Pt 5):745-54
1	J:203117 Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA, A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. Hum Mol Genet. 2014 Jan 1;23(1):194-208
1	J:316793 Matalova E, Lesot H, Svandova E, Vanden Berghe T, Sharpe PT, Healy C, Vandenabeele P, Tucker AS, Caspase-7 participates in differentiation of cells forming dental hard tissues. Dev Growth Differ. 2013 Jun;55(5):615-21
1*	J:341326 Nag P, Inubushi T, Sasaki JI, Murotani T, Kusano S, Nakanishi Y, Shiraishi Y, Kurosaka H, Imazato S, Yamaguchi Y, Yamashiro T, Tmem2 Deficiency Leads to Enamel Hypoplasia and Soft Enamel in Mouse. J Dent Res. 2023 Sep;102(10):1162-1171
1	J:17058 Nakamura M, Bringas P Jr, Nanci A, Zeichner-David M, Ashdown B, Slavkin HC, Translocation of enamel proteins from inner enamel epithelia to odontoblasts during mouse tooth development. Anat Rec. 1994 Mar;238(3):383-96
1	J:309378 Naveau A, Zhang B, Meng B, Sutherland MT, Prochazkova M, Wen T, Marangoni P, Jones KB, Cox TC, Ganss B, Jheon AH, Klein OD, Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor. J Bone Miner Res. 2017 Nov;32(11):2219-2231
1*	J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87
1	J:103753 Rios H, Koushik SV, Wang H, Wang J, Zhou HM, Lindsley A, Rogers R, Chen Z, Maeda M, Kruzynska-Frejtag A, Feng JQ, Conway SJ, periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol. 2005 Dec;25(24):11131-44
1	J:267193 Sun Z, da Fontoura CSG, Moreno M, Holton NE, Sweat M, Sweat Y, Lee MK, Arbon J, Bidlack FB, Thedens DR, Nopoulos P, Cao H, Eliason S, Weinberg SM, Martin JF, Moreno-Uribe L, Amendt BA, FoxO6 regulates Hippo signaling and growth of the craniofacial complex. PLoS Genet. 2018 Oct;14(10):e1007675
1*	J:256805 Tao J, Zhai Y, Park H, Han J, Dong J, Xie M, Gu T, Lewi K, Ji F, Jia W, Circadian Rhythm Regulates Development of Enamel in Mouse Mandibular First Molar. PLoS One. 2016;11(8):e0159946
1*	J:270176 Tian Z, Lv X, Zhang M, Wang X, Chen Y, Tang P, Xu P, Zhang L, Wu B, Zhang L, Deletion of epithelial cell-specific Cdc42 leads to enamel hypermaturation in a conditional knockout mouse model. Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2623-2632
1	J:178707 Wang SK, Komatsu Y, Mishina Y, Potential contribution of neural crest cells to dental enamel formation. Biochem Biophys Res Commun. 2011 Nov 11;415(1):114-9
1	J:94518 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I, Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov;7(5):719-30
1*	J:332246 Xie F, Zhu X, Liu X, Chen H, Wang J, N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis. J Biol Chem. 2022 Dec;298(12):102715
1	J:97520 Yamada A, Fukumoto E, Kamasaki Y, Ida-Yonemochi H, Saku T, Fujiwara T, Fukumoto S, GD3 synthase gene found expressed in dental epithelium and shown to regulate cell proliferation. Arch Oral Biol. 2005 Apr;50(4):393-9
1*	J:39157 Zeichner-David M, Vo H, Tan H, Diekwisch T, Berman B, Thiemann F , Alcocer MD , Hsu P , Wang T , Eyna J , Caton J , Slavkin HC , MacDougall M, Timing of the expression of enamel gene products during mouse tooth development. Int J Dev Biol. 1997 Feb;41(1):27-38
1	J:319643 Zhang B, Meng B, Viloria E, Naveau A, Ganss B, Jheon AH, The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal. Cells Tissues Organs. 2018;205(2):63-71
1	J:274043 Zhang H, Takeda H, Tsuji T, Kamiya N, Kunieda T, Mochida Y, Mishina Y, Loss of Function of Evc2 in Dental Mesenchyme Leads to Hypomorphic Enamel. J Dent Res. 2017 Apr;96(4):421-429
1*	J:139188 Zhao H, Oka K, Bringas P, Kaartinen V, Chai Y, TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
1	J:266585 Zheng J, Nie X, He L, Yoon AJ, Wu L, Zhang X, Vats M, Schiff MD, Xiang L, Tian Z, Ling J, Mao JJ, Epithelial Cdc42 Deletion Induced Enamel Organ Defects and Cystogenesis. J Dent Res. 2018 Nov;97(12):1346-1354
1	J:330612 Zheng X, Huang W, He Z, Li Y, Li S, Song Y, Effects of Fam83h truncation mutation on enamel developmental defects in male C57/BL6J mice. Bone. 2022 Oct 20;166:116595
1	J:50541 Zhou HM, Nichols A, Wohlwend A, Bolon I, Vassalli JD, Extracellular proteolysis alters tooth development in transgenic mice expressing urokinase-type plasminogen activator in the enamel organ. Development. 1999 Feb;126(5):903-12